AKR1A1 antibody (AA 2-325)

Catalog No. ABIN7143637

Product Details anti-AKR1A1 Antibody

Target: AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))

Binding Specificity: AA 2-325

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Alcohol dehydrogenase [NADP(+)] protein (2-325AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AKR1A1

Target: AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))

Alternative Name: AKR1A1 (AKR1A1 Products)

Synonyms: akr1a1 antibody, zgc:100940 antibody, aldr1 antibody, alr antibody, arm antibody, dd3 antibody, AKR1A1 antibody, zgc:110225 antibody, ALDR1 antibody, ALR antibody, ARM antibody, DD3 antibody, Akr1a4 antibody, 2610201A18Rik antibody, ALR1 antibody, Alr antibody, aldo-keto reductase family 1, member A1a (aldehyde reductase) antibody, aldo-keto reductase family 1, member A1 (aldehyde reductase) antibody, aldo-keto reductase family 1 member A1 antibody, aldo-keto reductase family 1, member A1b (aldehyde reductase) antibody, aldehyde reductase antibody, aldo-keto reductase family 1, member A1 (aldehyde reductase) L homeolog antibody, akr1a1a antibody, akr1a1 antibody, AKR1A1 antibody, akr1a1b antibody, Akr1a1 antibody, akr1a1.L antibody

Background:

Background: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).

Aliases: AK1A1_HUMAN antibody, Akr1a1 antibody, Alcohol dehydrogenase [NADP+] antibody, Alcohol dehydrogenase antibody, Aldehyde reductase antibody, Aldo keto reductase family 1 member A1 (aldehyde reductase) antibody, Aldo-keto reductase family 1 member A1 antibody, ALDR1 antibody, ALR antibody, ARM antibody, DD3 antibody, MGC12529 antibody, MGC1380 antibody

UniProt: P14550

Pathways: Monocarboxylic Acid Catabolic Process