NDC80 antibody (AA 545-642)

Catalog No. ABIN564521

There is 1 publication for this product available. The Mouse Monoclonal anti-NDC80 antibody is suitable to detect NDC80 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for NDC80 antibody (AA 545-642) (ABIN564521)

Target: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NDC80 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1A10

Product Details anti-NDC80 Antibody

Binding Specificity: AA 545-642

Purpose: Mouse monoclonal antibody raised against a partial recombinant KNTC2.

Sequence: TVNQGLSEAM NELDAVQREY QLVVQTTTEE RRKVGNNLQR LLEMVATHVG SVEKHLEEQI AKVDREYEEC MSEDLSENIK EIRDKYEKKA TLIKSSEE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: KNTC2 (AAH35617, 545 a.a. ~ 642 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-NDC80 antibody (ABIN564521)

Scott, Nogueira, Heffernan, van Doorn, Dhakal, Hanna, Min, Jaskelioff, Xiao, Wu, Cameron, Perry, Zeid, Feinberg, Kim, Vande Woude, Granter, Bosenberg, Chu, DePinho, Rimm, Chin: "Proinvasion metastasis drivers in early-stage melanoma are oncogenes." in: Cancer cell, Vol. 20, Issue 1, pp. 92-103, (2011) (PubMed).

Target Details for NDC80

Target: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Alternative Name: NDC80

Background: Full Gene Name: NDC80 homolog, kinetochore complex component (S. cerevisiae)
Synonyms: HEC,HEC1,KNTC2,TID3,hsNDC80

Gene ID: 10403

Pathways: Maintenance of Protein Location