SIVA1 antibody (AA 1-110)

Catalog No. ABIN564613

This Mouse Polyclonal antibody specifically detects SIVA1 in ELISA. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for SIVA1 antibody (AA 1-110) (ABIN564613)

Target: SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This SIVA1 antibody is un-conjugated

Application: ELISA

Product Details anti-SIVA1 Antibody

Binding Specificity: AA 1-110

Purpose: Mouse polyclonal antibody raised against a full-length recombinant SIVA.

Sequence: MPKRSCPFAD VAPLQLKVRV SQRELSRGVC AERYSQEVFD PSGVASIACS SCVRPVDGKA VCGQCERALC GQCVRTCWGC GSVACTLCGL VDCSDMYEKV LCTSCAMFET

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SIVA (AAH34562, 1 a.a. ~ 110 a.a) full-length recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SIVA1 antibody (ABIN564613)

Wang, Zha, Zhao, Jiang, Du, Tam, Mei, Wu: "Siva1 inhibits p53 function by acting as an ARF E3 ubiquitin ligase." in: Nature communications, Vol. 4, pp. 1551, (2013) (PubMed).

Kalousek, Brodska, Otevrelova, Röselova: "Actinomycin D upregulates proapoptotic protein Puma and downregulates Bcl-2 mRNA in normal peripheral blood lymphocytes." in: Anti-cancer drugs, Vol. 18, Issue 7, pp. 763-72, (2007) (PubMed).

Diegmann, Junker, Loncarevic, Michel, Schimmel, von Eggeling: "Immune escape for renal cell carcinoma: CD70 mediates apoptosis in lymphocytes." in: Neoplasia (New York, N.Y.), Vol. 8, Issue 11, pp. 933-8, (2006) (PubMed).

Target Details for SIVA1

Target: SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))

Alternative Name: SIVA1

Background: Full Gene Name: SIVA1, apoptosis-inducing factor
Synonyms: CD27BP,SIVA,Siva-1,Siva-2

Gene ID: 10572

Pathways: Positive Regulation of Endopeptidase Activity