POLD3 antibody (AA 357-466)

Catalog No. ABIN564666

Product Details anti-POLD3 Antibody

Target: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Binding Specificity: AA 357-466

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This POLD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against a partial recombinant POLD3.

Sequence: PPLEPVPKTE PEPPSVKSSS GENKRKRKRV LKSKTYLDGE GCIVTEKVYE SESCTDSEEE LNMKTSSVHR PPAMTVKKEP REERKGPKKG TAALGKANRQ VSITGFFQRK

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: POLD3 (NP_006582, 357 a.a. ~ 466 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3E2

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-POLD3 antibody (ABIN564666)

Bursomanno, Beli, Khan, Minocherhomji, Wagner, Bekker-Jensen, Mailand, Choudhary, Hickson, Liu: "Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells." in: DNA repair, Vol. 25, pp. 84-96, (2014) (PubMed).

Target Details for POLD3

Target: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Alternative Name: POLD3 (POLD3 Products)

Background: Full Gene Name: polymerase (DNA-directed), delta 3, accessory subunit
Synonyms: KIAA0039,MGC119642,MGC119643,P66,P68

Gene ID: 10714

NCBI Accession: NM_006591

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA