POLD3 antibody (AA 197-466)
-
- Target See all POLD3 Antibodies
- POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))
-
Binding Specificity
- AA 197-466
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This POLD3 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- ASKAAAKTQE TNKETKTEAK EVTNASAAGN KAPGKGNMMS NFFGKAAMNK FKVNLDSEQA VKEEKIVEQP TVSVTEPKLA TPAGLKKSSK KAEPVKVLQK EKKRGKRVAL SDDETKETEN MRKKRRRIKL PESDSSEDEV FPDSPGAYEA ESPSPPPPPS PPLEPVPKTE PEPPSVKSSS GENKRKRKRV LKSKTYLDGE GCIVTEKVYE SESCTDSEEE LNMKTSSVHR PPAMTVKKEP REERKGPKKG TAALGKANRQ VSITGFFQRK
- Cross-Reactivity
- Human, Mouse
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 197-466 of human POLD3 (NP_006582.1).
- Isotype
- IgG
-
-
- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:100
- Comment
-
HIGH QUALITY
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
: "
-
RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
-
- Target
- POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))
- Alternative Name
- POLD3 (POLD3 Products)
- Synonyms
- zgc:136471 antibody, P66 antibody, P68 antibody, 2410142G14Rik antibody, C85233 antibody, polymerase (DNA-directed), delta 3, accessory subunit L homeolog antibody, polymerase (DNA-directed), delta 3, accessory subunit antibody, DNA polymerase delta 3, accessory subunit antibody, pold3.L antibody, pold3 antibody, POLD3 antibody, Pold3 antibody
- Background
- This gene encodes the 66- kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene.,POLD3,P66,P68,PPP1R128,Epigenetics & Nuclear Signaling,DNA Damage & Repair,POLD3
- Molecular Weight
- 39 kDa/46 kDa/51 kDa
- Gene ID
- 10714
- UniProt
- Q15054
- Pathways
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
-