POLD3 antibody

Catalog No. ABIN7075130

Product Details anti-POLD3 Antibody

Target: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLD3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinantproteincorrespondingto Mouse POLD3

Application Details

Application Notes: IHC/IF (M,R) 1:400-1:1000/1:400-1:1200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for POLD3

Target: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Alternative Name: POLD3 (POLD3 Products)

Synonyms: zgc:136471 antibody, P66 antibody, P68 antibody, 2410142G14Rik antibody, C85233 antibody, polymerase (DNA-directed), delta 3, accessory subunit L homeolog antibody, polymerase (DNA-directed), delta 3, accessory subunit antibody, DNA polymerase delta 3, accessory subunit antibody, pold3.L antibody, pold3 antibody, POLD3 antibody, Pold3 antibody

Background: In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases, namely DNA pol alpha, beta, delta and epsilon. DNA pol delta and DNA pol epsilon are multisubunit enzymes, with DNA pol delta consisting of two subunits which interact with the sliding DNA clamp protein PCNA.

UniProt: Q9EQ28

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA