SIX2 antibody (AA 1-291)

Catalog No. ABIN564682

Product Details anti-SIX2 Antibody

Target: SIX2 (SIX Homeobox 2 (SIX2))

Binding Specificity: AA 1-291

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, RNA Interference (RNAi)

Purpose: Mouse monoclonal antibody raised against a full length recombinant SIX2.

Sequence: MSMLPTFGFT QEQVACVCEV LQQGGNIERL GRFLWSLPAC EHLHKNESVL KAKAVVAFHR GNFRELYKIL ESHQFSPHNH AKLQQLWLKA HYIEAEKLRG RPLGAVGKYR VRRKFPLPRS IWDGEETSYC FKEKSRSVLR EWYAHNPYPS PREKRELTEA TGLTTTQVSN WFKNRRQRDR AAEAKERENN ENSNSNSHNP LNGSGKSVLG SSEDEKTPSG TPDHSSSSPA LLLSPPPPGL PSLHSLGHPP GPSAVPVPVP GGGGADPLQH HHGLQDSILN PMSANLVDLG S

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SIX2 (AAH24033, 1 a.a. ~ 291 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3D7

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SIX2 antibody (ABIN564682)

Wainwright, Wilhelm, Combes, Little, Koopman: "ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation." in: Developmental biology, Vol. 404, Issue 2, pp. 88-102, (2015) (PubMed).

Mao, Francis-West, Irvine: "Fat4/Dchs1 signaling between stromal and cap mesenchyme cells influences nephrogenesis and ureteric bud branching." in: Development (Cambridge, England), Vol. 142, Issue 15, pp. 2574-85, (2015) (PubMed).

Hilliard, Yao, El-Dahr: "Mdm2 is required for maintenance of the nephrogenic niche." in: Developmental biology, Vol. 387, Issue 1, pp. 1-14, (2014) (PubMed).

Lee, Kim, Ryu, Lee, Yang, Jeong, Kim, Lee, Kim, Hajjar, Park: "Transcription coactivator Eya2 is a critical regulator of physiological hypertrophy." in: Journal of molecular and cellular cardiology, Vol. 52, Issue 3, pp. 718-26, (2012) (PubMed).

Murphy, Pierce, de Caestecker, Taylor, Anderson, Perantoni, de Caestecker, Lovvorn: "SIX2 and CITED1, markers of nephronic progenitor self-renewal, remain active in primitive elements of Wilms' tumor." in: Journal of pediatric surgery, Vol. 47, Issue 6, pp. 1239-49, (2012) (PubMed).

Target Details for SIX2

Target: SIX2 (SIX Homeobox 2 (SIX2))

Alternative Name: SIX2 (SIX2 Products)

Background: Full Gene Name: SIX homeobox 2
Synonyms:

Gene ID: 10736

Pathways: Protein targeting to Nucleus