Calpain 9 antibody (AA 591-690)

Catalog No. ABIN564689

The Mouse Monoclonal anti-Calpain 9 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect Calpain 9 in samples from Human. There are 4+ publications available.

Quick Overview for Calpain 9 antibody (AA 591-690) (ABIN564689)

Target: Calpain 9 (CAPN9)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calpain 9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3A6

Product Details anti-Calpain 9 Antibody

Binding Specificity: AA 591-690

Purpose: Mouse monoclonal antibody raised against a partial recombinant CAPN9.

Sequence: DKLKQWINLF LRFDADKSGT MSTYELRTAL KAAGFQLSSH LLQLIVLRYA DEELQLDFDD FLNCLVRLEN ASRVFQALST KNKEFIHLNI NEFIHLTMNI

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CAPN9 (NP_006606, 591 a.a. ~ 690 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Calpain 9 antibody (ABIN564689)

Davis, Martin, Patel, Green, Rakha, Ellis, Storr: "Low calpain-9 is associated with adverse disease-specific survival following endocrine therapy in breast cancer." in: BMC cancer, Vol. 14, pp. 995, (2015) (PubMed).

Storr, Pu, Davis, Lobo, Reece-Smith, Parsons, Madhusudan, Martin: "Expression of the calpain system is associated with poor clinical outcome in gastro-oesophageal adenocarcinomas." in: Journal of gastroenterology, Vol. 48, Issue 11, pp. 1213-21, (2013) (PubMed).

Chen, Nguyen, Shively: "Role of calpain-9 and PKC-delta in the apoptotic mechanism of lumen formation in CEACAM1 transfected breast epithelial cells." in: Experimental cell research, Vol. 316, Issue 4, pp. 638-48, (2010) (PubMed).

Hata, Abe, Suzuki, Kitamura, Toyama-Sorimachi, Abe, Sakimura, Sorimachi: "Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense." in: PLoS genetics, Vol. 6, Issue 7, pp. e1001040, (2010) (PubMed).

Target Details for Calpain 9

Target: Calpain 9 (CAPN9)

Alternative Name: CAPN9

Background: Full Gene Name: calpain 9
Synonyms: GC36,nCL-4

Gene ID: 10753

NCBI Accession: NM_006615