BMP4 antibody

Catalog No. ABIN5647052

This anti-BMP4 antibody is a Rabbit Polyclonal antibody detecting BMP4 in WB and ELISA (Capture). Suitable for Human.

Quick Overview for BMP4 antibody (ABIN5647052)

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA (Capture)

Product Details anti-BMP4 Antibody

Purification: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids S293-R408 was used as the immunogen for the BMP4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the BMP4 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture, human recombinant protein): 0.1-0.5 μg/mL (BSA-free formulation available)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the BMP4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for BMP4

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Alternative Name: BMP4 / Bone morphogenetic protein 4

Background: Bone morphogenetic protein 4 is a protein that in humans is encoded by BMP4 gene. It is found on chromosome 14q22-q23. The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

UniProt: P12644

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development