HNRNPA1 antibody (AA 8-42)

Catalog No. ABIN5647145

This anti-HNRNPA1 antibody is a Rabbit Polyclonal antibody detecting HNRNPA1 in WB and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for HNRNPA1 antibody (AA 8-42) (ABIN5647145)

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HNRNPA1 Antibody

Binding Specificity: AA 8-42

Purification: Antigen affinity purified

Immunogen: Amino acids 8-42 (KEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTD-human) were used as the immunogen for the hnRNP A1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the hnRNP A1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the hnRNP A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for HNRNPA1

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Alternative Name: hnRNP A1

Background: Heterogeneous nuclear ribonucleoprotein A1 is a protein that in humans is encoded by the HNRNPA1 gene. This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.

UniProt: P09651