IL23R antibody

Catalog No. ABIN5647308

This Rabbit Polyclonal antibody specifically detects IL23R in WB and ELISA (Capture). It exhibits reactivity toward Mouse and Rat.

Quick Overview for IL23R antibody (ABIN5647308)

Target: IL23R (Interleukin 23 Receptor (IL23R))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL23R antibody is un-conjugated

Application: Western Blotting (WB), ELISA (Capture)

Product Details anti-IL23R Antibody

Cross-Reactivity (Details): Expected species reactivity: Human

Purification: Antigen affinity purified

Immunogen: A recombinant mouse protein corresponding to amino acids I25-D233 was used as the immunogen for the Il23r antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Il23r antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture: recombinant mouse protein): 0.1-0.5 μg/mL (BSA-free format available)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Il23r antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for IL23R

Target: IL23R (Interleukin 23 Receptor (IL23R))

Alternative Name: Il-23 receptor / Il23r

Background: Interleukin 23 receptor is a type I cytokine receptor. IL23R is its human gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

UniProt: Q8K4B4

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation