MYBPC3 antibody

Catalog No. ABIN5647401

Product Details anti-MYBPC3 Antibody

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYBPC3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids Q1070-H1123 was used as the immunogen for the MYBPC3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MYBPC3 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the MYBPC3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for MYBPC3

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Alternative Name: MYBPC3 (MYBPC3 Products)

Synonyms: MGC114614 antibody, hm:zehn0716 antibody, im:6900815 antibody, zgc:152717 antibody, zgc:158442 antibody, fhc antibody, cmh4 antibody, mybp-c antibody, CMH4 antibody, FHC antibody, MYBP-C antibody, myosin binding protein C, cardiac S homeolog antibody, myosin binding protein C, cardiac antibody, mybpc3.S antibody, MYBPC3 antibody, mybpc3 antibody, Mybpc3 antibody

Background: The myosin-binding protein C, cardiac-type is a protein that in humans is encode by the MYBPC3 gene. MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

UniProt: Q14896