RALBP1 antibody (AA 1-655)

Catalog No. ABIN564745

This Mouse Monoclonal antibody specifically detects RALBP1 in WB, IP and ELISA. It exhibits reactivity toward Human and has been mentioned in 6+ publications.

Quick Overview for RALBP1 antibody (AA 1-655) (ABIN564745)

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RALBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA

Clone: 2A1

Product Details anti-RALBP1 Antibody

Binding Specificity: AA 1-655

Purpose: Mouse monoclonal antibody raised against a full length recombinant RALBP1.

Sequence: MTECFLPPTS SPSEHRRVEH GSGLTRTPSS EEISPTKFPG LYRTGEPSPP HDILHEPPDV VSDDEKDHGK KKGKFKKKEK RTEGYAAFQE DSSGDEAESP SKMKRSKGIH VFKKPSFSKK KEKDFKIKEK PKEEKHKEEK HKEEKHKEKK SKDLTAADVV KQWKEKKKKK KPIQEPEVPQ IDVPNLKPIF GIPLADAVER TMMYDGIRLP AVFRECIDYV EKYGMKCEGI YRVSGIKSKV DELKAAYDRE ESTNLEDYEP NTVASLLKQY LRDLPENLLT KELMPRFEEA CGRTTETEKV QEFQRLLKEL PECNYLLISW LIVHMDHVIA KELETKMNIQ NISIVLSPTV QISNRVLYVF FTHVQELFGN VVLKQVMKPL RWSNMATMPT LPETQAGIKE EIRRQEFLLN CLHRDLQGGI KDLSKEERLW EVQRILTALK RKLREAKRQE CETKIAQEIA SLSKEDVSKE EMNENEEVIN ILLAQENEIL TEQEELLAME QFLRRQIASE KEEIERLRAE IAEIQSRQQH GRSETEEYSS ESESESEDEE ELQIILEDLQ RQNEELEIKN NHLNQAIHEE REAIIELRVQ LRLLQMQRAK AEQQAQEDEE PEWRGGAVQP PRDGVLEPKA AREQPKAGKE PAKPSPSRDR KETSI

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RALBP1 (AAH13126.1, 1 a.a. ~ 655 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RALBP1 antibody (ABIN564745)

Tazat, Harsat, Goldshmid-Shagal, Ehrlich, Henis: "Dual effects of Ral-activated pathways on p27 localization and TGF-? signaling." in: Molecular biology of the cell, Vol. 24, Issue 11, pp. 1812-24, (2013) (PubMed).

Fillatre, Delacour, Van Hove, Bagarre, Houssin, Soulika, Veitia, Moreau: "Dynamics of the subcellular localization of RalBP1/RLIP through the cell cycle: the role of targeting signals and of protein-protein interactions." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 5, pp. 2164-74, (2012) (PubMed).

Neel, Rossman, Martin, Hayes, Yeh, Der: "The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector." in: Molecular and cellular biology, Vol. 32, Issue 8, pp. 1374-86, (2012) (PubMed).

Kidd, Snider, Martin, Graboski, Der, Cox: "Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation." in: International journal of radiation oncology, biology, physics, Vol. 78, Issue 1, pp. 205-12, (2010) (PubMed).

Smith, Oxford, Baras, Owens, Havaleshko, Brautigan, Safo, Theodorescu: "Expression of ral GTPases, their effectors, and activators in human bladder cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 13, pp. 3803-13, (2007) (PubMed).

Herlevsen, Theodorescu: "Mass spectroscopic phosphoprotein mapping of Ral binding protein 1 (RalBP1/Rip1/RLIP76)." in: Biochemical and biophysical research communications, Vol. 362, Issue 1, pp. 56-62, (2007) (PubMed).

Target Details for RALBP1

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Alternative Name: RALBP1

Background: Full Gene Name: ralA binding protein 1
Synonyms: RIP1,RLIP1,RLIP76

Gene ID: 10928