ACCN4 antibody (AA 23-52)
Quick Overview for ACCN4 antibody (AA 23-52) (ABIN5647477)
Target
See all ACCN4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 23-52
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 23-52 from the human protein was used as the immunogen for this ASIC4 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Western blot: 1:1000
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Restrictions
- For Research Use only
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the ASIC4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))
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Alternative Name
- ACCN4 / ASIC4
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Background
- This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.
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UniProt
- Q96FT7
Target
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