ADRM1 antibody (AA 18-407)

Catalog No. ABIN564790

This Mouse Monoclonal antibody specifically detects ADRM1 in WB, ELISA, IF and IP. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for ADRM1 antibody (AA 18-407) (ABIN564790)

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADRM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 3C6

Product Details anti-ADRM1 Antibody

Binding Specificity: AA 18-407

Purpose: Mouse monoclonal antibody raised against a full length recombinant ADRM1.

Sequence: ASNKYLVEFR AGKMSLKGTT VTPDKRKGLV YIQQTDDSLI HFCWKDRTSG NVEDDLIIFP DDCEFKRVPQ CPSGRVYVLK FKAGSKRLFF WMQEPKTDQD EEHCRKVNEY LNNPPMPGAL GASGSSGHEL SALGGEGGLQ SLLGNMSHSQ LMQLIGPAGL GGLGGLGALT GPGLASLLGS SGPPGSSSSS SSRSQSAAVT PSSTTSSTRA TPAPSAPAAA SATSPSPAPS SGNGASTAAS PTQPIQLSDL QSILATMNVP AGPAGGQQVD LASVLAPEIM APILANADVQ ERLLPYLPSG ESLPQTADEI QNTLTSPQFQ QALGMFSAAL ASGQLGPLMC QFGLPAEAVE AANKGDVEAF AKAMQNNAKP EQKEGDTKDK KDEEEDMSLD

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ADRM1 (AAH17245.1, 18 a.a. ~ 407 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ADRM1 antibody (ABIN564790)

Huang, Ratovitski: "Phospho-?Np63?/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells." in: Aging, Vol. 2, Issue 12, pp. 959-68, (2011) (PubMed).

Pece, Tosoni, Confalonieri, Mazzarol, Vecchi, Ronzoni, Bernard, Viale, Pelicci, Di Fiore: "Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content." in: Cell, Vol. 140, Issue 1, pp. 62-73, (2010) (PubMed).

Huang, Ratovitski: "Phosphorylated TP63 induces transcription of RPN13, leading to NOS2 protein degradation." in: The Journal of biological chemistry, Vol. 285, Issue 53, pp. 41422-31, (2010) (PubMed).

Target Details for ADRM1

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Alternative Name: ADRM1

Background: Full Gene Name: adhesion regulating molecule 1
Synonyms: ARM1,GP110,MGC29536,Rpn13

Gene ID: 11047

Pathways: Positive Regulation of Endopeptidase Activity