TRAIL antibody

Catalog No. ABIN5647921

The Rabbit Polyclonal anti-TRAIL antibody has been validated for WB and ELISA (Capture). It is suitable to detect TRAIL in samples from Human.

Quick Overview for TRAIL antibody (ABIN5647921)

Target: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAIL antibody is un-conjugated

Application: Western Blotting (WB), ELISA (Capture)

Product Details anti-TRAIL Antibody

Purification: Antigen affinity purified

Immunogen: A recombinant protein corresponding to amino acids N40-A272 was used as the immunogen for the TRAIL antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TRAIL antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture, human recombinant protein): 0.1-0.5 μg/mL (BSA-free format available)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the TRAIL antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for TRAIL

Target: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Alternative Name: TRAIL

Background: TNF-related apoptosis-inducing ligand (TRAIL), is a protein functioning as a ligand that induces the process of cell death called apoptosis. TRAIL has also been designated CD253 (cluster of differentiation 253). It is a member of Tumor Necrosis Factor Ligand Superfamily. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL has got 281 amino acid proteins. TRAIL mRNA is expressed at significant levels in most normal tissues. TRAIL binds to the death receptors DR4 (TRAIL-RI) and DR5 (TRAIL-RII) and the receptors DcR1 and DcR2, leading to activation of specific kinases and transcription of genes.

UniProt: P50591

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity