UBE2C antibody (AA 70-179)

Catalog No. ABIN564800

Product Details anti-UBE2C Antibody

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Binding Specificity: AA 70-179

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UBE2C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a partial recombinant UBE2C.

Sequence: AGTVYEDLRY KLSLEFPSGY PYNAPTVKFL TPCYHPNVDT QGNICLDILK EKWSALYDVR TILLSIQSLL GEPNIDSPLN THAAELWKNP TAFKKYLQET YSKQVTSQEP

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: UBE2C (NP_008950, 70 a.a. ~ 179 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 9D3

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-UBE2C antibody (ABIN564800)

Castelblanco, Zafon, Maravall, Gallel, Martinez, Capel, Bella, Halperin, Temprana, Iglesias, Puig-Domingo, Robledo, Matias-Guiu, Mauricio: "APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions." in: Thyroid : official journal of the American Thyroid Association, Vol. 27, Issue 1, pp. 59-66, (2016) (PubMed).

Chou, Huang, Jhuang, Pan, Peng, Cheng, Chen, Chen, Chang: "Ubiquitin-conjugating enzyme UBE2C is highly expressed in breast microcalcification lesions." in: PLoS ONE, Vol. 9, Issue 4, pp. e93934, (2014) (PubMed).

Fristrup, Birkenkamp-Demtröder, Reinert, Sanchez-Carbayo, Segersten, Malmström, Palou, Alvarez-Múgica, Pan, Ulhøi, Borre, Ørntoft, Dyrskjøt: "Multicenter validation of cyclin D1, MCM7, TRIM29, and UBE2C as prognostic protein markers in non-muscle-invasive bladder cancer." in: The American journal of pathology, Vol. 182, Issue 2, pp. 339-49, (2013) (PubMed).

Morikawa, Kawai, Abe, Kume, Homma, Fukayama: "UBE2C is a marker of unfavorable prognosis in bladder cancer after radical cystectomy." in: International journal of clinical and experimental pathology, Vol. 6, Issue 7, pp. 1367-74, (2013) (PubMed).

Guo, Li, Yang, Zhou, Zhang, Zhao: "Oligonucleotide microarray identifies genes differentially expressed during tumorigenesis of DMBA-induced pancreatic cancer in rats." in: PLoS ONE, Vol. 8, Issue 12, pp. e82910, (2013) (PubMed).

Jiang, Wang, Bao, Qian, Wu, Hu, Lu: "A study of UbcH10 expression and its association with recurrence of meningiomas." in: Journal of surgical oncology, Vol. 106, Issue 3, pp. 327-31, (2012) (PubMed).

Chen, Chen, Hu, Jing, Cao, Liu: "Association of clinicopathological features with UbcH10 expression in colorectal cancer." in: Journal of cancer research and clinical oncology, Vol. 136, Issue 3, pp. 419-26, (2010) (PubMed).

Jiang, Huang, Lu, Luo, Hu, Liu, Chen, Han: "Expression of ubiquitin-conjugating enzyme E2C/UbcH10 in astrocytic tumors." in: Brain research, Vol. 1201, pp. 161-6, (2008) (PubMed).

Target Details for UBE2C

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Alternative Name: UBE2C (UBE2C Products)

Background: Full Gene Name: ubiquitin-conjugating enzyme E2C
Synonyms: UBCH10,dJ447F3.2

Gene ID: 11065

NCBI Accession: NM_007019

Pathways: Ubiquitin Proteasome Pathway