MTUS1 antibody (AA 1-240)

Catalog No. ABIN566122

This Mouse Monoclonal antibody specifically detects MTUS1 in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 7+ publications.

Quick Overview for MTUS1 antibody (AA 1-240) (ABIN566122)

Target: MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MTUS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1C7

Product Details anti-MTUS1 Antibody

Binding Specificity: AA 1-240

Purpose: Mouse monoclonal antibody raised against a full length recombinant MTUS1.

Sequence: MQLQEQFDNL NAAHETSKLE IEASHSEKLE LLTKAYEASL SEIKKGHEIE KKSLEDLLSE KQESLEKQIN DLKSENDALN EKLKSEEQKR RAREKANLKN PQIMYLEQEL ESLKAVLEIK NEKLHQQDIK LMKMGKLVDN NTALVDKLKR FQQENEELKA RMDKHMAISR QLSTEQAVLQ ESLEKESKVN KRLSMENEEL LWKLHNGDLC SPKRSPTSSA IPLQSPRNSG SFPSPSISPR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: MTUS1 (AAH33842, 1 a.a. ~ 240 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MTUS1 antibody (ABIN566122)

Zhao, He, Liu, Ding, Zhou, Wang: "Angiotensin II type 2 receptor-interacting protein 3a suppresses proliferation, migration and invasion in tongue squamous cell carcinoma via the extracellular signal-regulated kinase-Snai2 pathway." in: Oncology letters, Vol. 11, Issue 1, pp. 340-344, (2016) (PubMed).

Shinoda, Luijten, Hasegawa, Hong, Sonne, Kim, Xue, Chondronikola, Cypess, Tseng, Nedergaard, Sidossis, Kajimura: "Genetic and functional characterization of clonally derived adult human brown adipocytes." in: Nature medicine, Vol. 21, Issue 4, pp. 389-94, (2015) (PubMed).

Rogler, Hoja, Giedl, Ekici, Wach, Taubert, Goebell, Wullich, Stöckle, Lehmann, Petsch, Hartmann, Stoehr: "Loss of MTUS1/ATIP expression is associated with adverse outcome in advanced bladder carcinomas: data from a retrospective study." in: BMC cancer, Vol. 14, pp. 214, (2014) (PubMed).

Guimond, Battista, Nikjouitavabi, Carmel, Barres, Doueik, Fazli, Gleave, Sabbagh, Gallo-Payet: "Expression and role of the angiotensin II AT2 receptor in human prostate tissue: in search of a new therapeutic option for prostate cancer." in: The Prostate, Vol. 73, Issue 10, pp. 1057-68, (2013) (PubMed).

Ding, Zhang, Cai, Li, Zheng, Jin, Yu, Wang, Zhou: "Down-regulation of tumor suppressor MTUS1/ATIP is associated with enhanced proliferation, poor differentiation and poor prognosis in oral tongue squamous cell carcinoma." in: Molecular oncology, Vol. 6, Issue 1, pp. 73-80, (2012) (PubMed).

Melcher, Hartmann, Zopf, Herterich, Wilke, Müller, Rosler, Kudlich, Al-Taie, Rosenwald, Katzenberger, Scholtka, Seibold, Rogoll, Scheppach, Scheurlen, Lührs: "LOH and copy neutral LOH (cnLOH) act as alternative mechanism in sporadic colorectal cancers with chromosomal and microsatellite instability." in: Carcinogenesis, Vol. 32, Issue 4, pp. 636-42, (2011) (PubMed).

Rodrigues-Ferreira, Di Tommaso, Dimitrov, Cazaubon, Gruel, Colasson, Nicolas, Chaverot, Molinié, Reyal, Sigal-Zafrani, Terris, Delattre, Radvanyi, Perez, Vincent-Salomon, Nahmias: "8p22 MTUS1 gene product ATIP3 is a novel anti-mitotic protein underexpressed in invasive breast carcinoma of poor prognosis." in: PLoS ONE, Vol. 4, Issue 10, pp. e7239, (2009) (PubMed).

Target Details for MTUS1

Target: MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))

Alternative Name: MTUS1

Background: Full Gene Name: mitochondrial tumor suppressor 1
Synonyms: ATIP,DKFZp586D1519,DKFZp686F20243,FLJ14295,KIAA1288,MP44,MTSG1

Gene ID: 57509