IRX1 antibody (AA 424-479)

Catalog No. ABIN566348

The Mouse Polyclonal anti-IRX1 antibody has been validated for WB and ELISA. It is suitable to detect IRX1 in samples from Human. There are 3+ publications available.

Quick Overview for IRX1 antibody (AA 424-479) (ABIN566348)

Target: IRX1 (Iroquois Homeobox Protein 1 (IRX1))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This IRX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IRX1 Antibody

Binding Specificity: AA 424-479

Purpose: Mouse polyclonal antibody raised against a partial recombinant IRX1.

Sequence: NGDKASVRSS PTLPERDLVP RPDSPAQQLK SPFQPVRDNS LAPQEGTPRI LAALPS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: IRX1 (NP_077313, 424 a.a. ~ 479 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-IRX1 antibody (ABIN566348)

Zougman, Mann, Wisniewski: "Identification and characterization of a novel ubiquitous nucleolar protein 'NARR' encoded by a gene overlapping the rab34 oncogene." in: Nucleic acids research, Vol. 39, Issue 16, pp. 7103-13, (2011) (PubMed).

Guo, Guo, Zhi, Ji, Jiang, Zhang, Zhang, Zhang, Chen, Cai, Li, Yan, Gu, Liu, Zhu, Yu: "Helicobacter pylori induces promoter hypermethylation and downregulates gene expression of IRX1 transcription factor on human gastric mucosa." in: Journal of gastroenterology and hepatology, Vol. 26, Issue 11, pp. 1685-90, (2011) (PubMed).

Guo, Liu, Pan, Ni, Ji, Guo, Zhang, Wu, Jiang, Chen, Cai, Li, Zhang, Gu, Liu, Zhu, Yu: "Homeobox gene IRX1 is a tumor suppressor gene in gastric carcinoma." in: Oncogene, Vol. 29, Issue 27, pp. 3908-20, (2010) (PubMed).

Target Details for IRX1

Target: IRX1 (Iroquois Homeobox Protein 1 (IRX1))

Alternative Name: IRX1

Background: Full Gene Name: iroquois homeobox 1
Synonyms: IRX-5,IRXA1

Gene ID: 79192

NCBI Accession: NM_024337

Pathways: Tube Formation