Aryl Hydrocarbon Receptor antibody (AA 619-848)

Catalog No. ABIN5663909

This Rabbit Polyclonal antibody specifically detects Aryl Hydrocarbon Receptor in WB, IHC and IF. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for Aryl Hydrocarbon Receptor antibody (AA 619-848) (ABIN5663909)

Target: Aryl Hydrocarbon Receptor (AHR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aryl Hydrocarbon Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Aryl Hydrocarbon Receptor Antibody

Binding Specificity: AA 619-848

Sequence: LEQQQQHHQK QVVVEPQQQL CQKMKHMQVN GMFENWNSNQ FVPFNCPQQD PQQYNVFTDL HGISQEFPYK SEMDSMPYTQ NFISCNQPVL PQHSKCTELD YPMGSFEPSP YPTTSSLEDF VTCLQLPENQ KHGLNPQSAI ITPQTCYAGA VSMYQCQPEP QHTHVGQMQY NPVLPGQQAF LNKFQNGVLN ETYPAELNNI NNTQTTTHLQ PLHHPSEARP FPDLTSSGFL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 619-848 of human AHR (NP_001612.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Aryl Hydrocarbon Receptor antibody (ABIN5663909)

Liu, Zhou, Zhang, Ding, Du, Hu: "1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells." in: International journal of cancer, Vol. 143, Issue 6, pp. 1516-1529, (2018) (PubMed).

Target Details for Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Alternative Name: AHR

Background: The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm, upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.,AHR,bHLHe76,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Apoptosis,AHR

Molecular Weight: 96 kDa

Gene ID: 196

UniProt: P35869

Pathways: Regulation of Cell Size