GRHL2 antibody (AA 111-210)

Catalog No. ABIN566411

The Mouse Polyclonal anti-GRHL2 antibody has been validated for WB and ELISA. It is suitable to detect GRHL2 in samples from Human. There are 4+ publications available.

Quick Overview for GRHL2 antibody (AA 111-210) (ABIN566411)

Target: GRHL2 (Grainyhead-Like 2 (GRHL2))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This GRHL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GRHL2 Antibody

Binding Specificity: AA 111-210

Purpose: Mouse polyclonal antibody raised against a partial recombinant GRHL2.

Sequence: ENRVQVLKTV PVNLSLNQDH LENSKREQYS ISFPESSAII PVSGITVVKA EDFTPVFMAP PVHYPRGDGE EQRVVIFEQT QYDVPSLATH SAYLKDDQRS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GRHL2 (NP_079191, 111 a.a. ~ 210 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GRHL2 antibody (ABIN566411)

Werner, Frey, Riethdorf, Schulze, Alawi, Kling, Vafaizadeh, Sauter, Terracciano, Schumacher, Pantel, Assmann: "Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer." in: The Journal of biological chemistry, Vol. 288, Issue 32, pp. 22993-3008, (2013) (PubMed).

Chen, Xiao Liu, Oh, Shin, Kim, Jiang, Park, Kang: "Grainyhead-like 2 (GRHL2) inhibits keratinocyte differentiation through epigenetic mechanism." in: Cell death & disease, Vol. 3, pp. e450, (2012) (PubMed).

Chen, Dong, Shin, Kim, Oh, Park, Kang: "Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytes." in: The Journal of biological chemistry, Vol. 285, Issue 52, pp. 40852-63, (2010) (PubMed).

Kang, Chen, Kim, Kang, Park: "Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells." in: Oncogene, Vol. 28, Issue 4, pp. 565-74, (2009) (PubMed).

Target Details for GRHL2

Target: GRHL2 (Grainyhead-Like 2 (GRHL2))

Alternative Name: GRHL2

Background: Full Gene Name: grainyhead-like 2 (Drosophila)
Synonyms: BOM,DFNA28,FLJ11172,FLJ13782,MGC149294,MGC149295,TFCP2L3

Gene ID: 79977

NCBI Accession: NM_024915

Pathways: Tube Formation