FMNL2 antibody (AA 1-178)

Catalog No. ABIN566725

This Mouse Monoclonal antibody specifically detects FMNL2 in ELISA and WB. It exhibits reactivity toward Human and has been mentioned in 5+ publications.

Quick Overview for FMNL2 antibody (AA 1-178) (ABIN566725)

Target: FMNL2 (Formin-Like 2 (FMNL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FMNL2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Clone: 2B4

Product Details anti-FMNL2 Antibody

Binding Specificity: AA 1-178

Purpose: Mouse monoclonal antibody raised against a full length recombinant FMNL2.

Sequence: MDLTKREYTM HDHNTLLKEF ILNNEGKLKK LQDDAKIAQD AFDDVVKYFG ENPKTTPPSV FFPVFVRFVK AYKQAEEENE LRKKQEQALM EKLLEQEALM EQQDPKSPSH KSKRQQQELI AELRRRQVKD NRHVYEGKDG AIEDIITALK KNNITKFPNV HSRVRISSST PVVEDTQS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: FMNL2 (AAH36492, 1 a.a. ~ 178 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FMNL2 antibody (ABIN566725)

Liang, Guan, Zeng, Wang, Li, Zhang, Ding: "Down-regulation of formin-like 2 predicts poor prognosis in hepatocellular carcinoma." in: Human pathology, Vol. 42, Issue 11, pp. 1603-12, (2011) (PubMed).

Zhu, Zeng, Guan, Li, Deng, Bian, Ding, Liang: "FMNL2 is a positive regulator of cell motility and metastasis in colorectal carcinoma." in: The Journal of pathology, Vol. 224, Issue 3, pp. 377-88, (2011) (PubMed).

Kitzing, Wang, Pertz, Copeland, Grosse: "Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC." in: Oncogene, Vol. 29, Issue 16, pp. 2441-8, (2010) (PubMed).

Li, Zhu, Zeng, Wang, Zhang, Ding, Liang: "FMNL2 enhances invasion of colorectal carcinoma by inducing epithelial-mesenchymal transition." in: Molecular cancer research : MCR, Vol. 8, Issue 12, pp. 1579-90, (2010) (PubMed).

Zhu, Liang, Ding: "Overexpression of FMNL2 is closely related to metastasis of colorectal cancer." in: International journal of colorectal disease, Vol. 23, Issue 11, pp. 1041-7, (2008) (PubMed).

Target Details for FMNL2

Target: FMNL2 (Formin-Like 2 (FMNL2))

Alternative Name: FMNL2

Background: Full Gene Name: formin-like 2
Synonyms: FHOD2,FLJ37546

Gene ID: 114793