Recombinant Amyloid beta (4-10) (AA 1-42) antibody

Catalog No. ABIN5668013

Cited in 1 publication. The Mouse Monoclonal anti-Amyloid beta (4-10) antibody (Clone WO2) (ABIN5668013) specifically detects Amyloid beta (4-10) in ELISA, IHC (p) and WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant Amyloid beta (4-10) (AA 1-42) antibody (ABIN5668013)

Target: Amyloid beta (4-10)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Clone: WO2

Product Details

Binding Specificity: AA 1-42

Purpose: Anti-Amyloid beta (aa 4-10) [WO2], Mouse IgG2a, kappa

Specificity: Recognises amino acid residues 4-10 of human Amyloid β.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogen: Synthetic peptides, corresponding to amino acids 1-42 of human beta amyloid, conjugated to KLH.

Isotype: IgG2a kappa

Application Details

Application Notes: This antibody binds to amyloid beta peptides and may be used in Western Blotting as well as ELISA and IHC. Youn et al. (PMID: 31077246) describes the use of an HRP-conjugate of the IgG2a version of WO2 in a diagnostic Multimer Detection System-Oligomeric Amyloid-β assay to measure oligomerization tendencies in the blood.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

References

Brai, Stuart, Badin, Greenfield: "A Novel Ex Vivo Model to Investigate the Underlying Mechanisms in Alzheimer's Disease." in: Frontiers in cellular neuroscience, Vol. 11, pp. 291, (2017) (PubMed).

Target Details

Target: Amyloid beta (4-10)

Background: Abeta

UniProt: P05067