Recombinant ED-B Domain of Fibronectin antibody

Catalog No. ABIN5668018

Product Details

Target: ED-B Domain of Fibronectin

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Surface Plasmon Resonance (SPR), Western Blotting (WB)

Purpose: Anti-Fibronectin [A2], Human IgG1, kappa

Specificity: This antibody binds to the ED-B domain of human fibronectin.

Characteristics:

Original Species of Ab: Human

Original Format of Ab: scFv

Purification: Protein A affinity purified

Immunogen: 2D-PAGE gel isolated human Extra-Domain containing fibronectin from lysate of human melanoma COLO-38 cells.

Clone: A2

Isotype: IgG1 kappa

Application Details

Application Notes: Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Extra domain-B containing fibronectin has been proposed marker of angiogenesis, has been shown to be expressed in a number of human cancers and in ocular neovascularization in patients with proliferative diabetic retinopathy.

Comment:

This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details

Target: ED-B Domain of Fibronectin

Background: FN, EDB(+) FN, ED-B domain of fibronectin, Extra domain-B containing fibronectin

UniProt: P02751