Recombinant ITGAL (Efalizumab Biosimilar) antibody

Catalog No. ABIN5668045

The Rabbit Chimeric anti-ITGAL (Efalizumab Biosimilar) antibody has been validated for BR and FACS. It is suitable to detect ITGAL (Efalizumab Biosimilar) in samples from Human.

Quick Overview for Recombinant ITGAL (Efalizumab Biosimilar) antibody (ABIN5668045)

Target: ITGAL (Efalizumab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This ITGAL (Efalizumab Biosimilar) antibody is un-conjugated

Application: Blocking Reagent (BR), Flow Cytometry (FACS)

Clone: Hu1124

Product Details anti-ITGAL (Efalizumab Biosimilar) Antibody

Purpose: Anti-CD11a [hu1124 (Efalizumab)], Rabbit IgG, kappa

Specificity: Binds to human LFA-1.

Characteristics:

Original Species of Ab: Human

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Purity: > 98 % as determined by SDS-PAGE

Endotoxin Level: Endotoxin is < 1.0 EU/mg as determined by the LAL method

Immunogen: Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.

Isotype: IgG kappa

Application Details

Application Notes: Efalizumab binds to the LFA-1 alpha I domain blocking the ICAM-1 binding site via steric hindrance.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for ITGAL (Efalizumab Biosimilar)

Target: ITGAL (Efalizumab Biosimilar)

Target Type: Biosimilar

Background: LFA-1, integrin alpha L

UniProt: P20701