Recombinant EGFR antibody
Quick Overview for Recombinant EGFR antibody (ABIN5668055)
Target
See all EGFR AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purpose
- Anti-EGFR [528], Rabbit IgG, kappa
-
Specificity
- Recognizes the extracellular domain of EGFR.
-
Characteristics
-
Original Species of Ab: Mouse
Original Format of Ab: IgG2a
-
Purification
- Protein A affinity purified
-
Immunogen
- Partially purified EGFR from A431 cells.
-
Isotype
- IgG kappa
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG2a format, for improved compatibility with existing reagents, assays and techniques.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % Proclin 300.
-
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
- EGFR (Epidermal Growth Factor Receptor (EGFR))
-
Alternative Name
- EGFR
-
Background
- ERBB, ERBB1, HER1, PIG61, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, proto-oncogene c-ErbB-1, receptor tyrosine-protein kinase erbB-1, epidermal growth f
-
UniProt
- P00533
-
Pathways
- NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
Target
-