Recombinant VEGF (Bevacizumab Biosimilar) antibody
Quick Overview for Recombinant VEGF (Bevacizumab Biosimilar) antibody (ABIN5668150)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
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Purpose
 - Anti-VEGF [Bevacizumab], Human IgG1, kappa
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Specificity
 - This antibody binds native and reduced human VEGF (isoform 165).
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Characteristics
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Original Species of Ab: Human
Original Format of Ab: IgG1
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Purification
 - Protein A affinity purified
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Purity
 - > 98 % as determined by SDS-PAGE
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Endotoxin Level
 - Endotoxin is < 1.0 EU/mg as determined by the LAL method
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Immunogen
 - Recombinant human VEGF.
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Isotype
 - IgG1 kappa
 
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Application Notes
 - This is a research-grade biosimilar against VEGF. VEGF is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.
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Comment
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NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
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Restrictions
 - For Research Use only
 
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Concentration
 - 1 mg/mL
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Buffer
 - PBS with 0.02 % Proclin 300.
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Preservative
 - ProClin
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Precaution of Use
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
 - 4 °C,-20 °C
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Storage Comment
 - Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
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- VEGF (Bevacizumab Biosimilar)
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Background
 - Ascular Endothelial Growth Factor, VEGF-A, VEGFA, Vascular Permeability Factor, VPF
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UniProt
 - P15692
 
Target
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