Recombinant CD3 epsilon antibody

Catalog No. ABIN5668184

This Mouse Monoclonal antibody specifically detects CD3 epsilon in FACS and Act. It exhibits reactivity toward Human.

Quick Overview for Recombinant CD3 epsilon antibody (ABIN5668184)

Target: CD3 epsilon (CD3E)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 epsilon antibody is un-conjugated

Application: Flow Cytometry (FACS), Activation (Act)

Clone: 12F6

Product Details anti-CD3 epsilon Antibody

Purpose: Anti-CD3 epsilon [12F6], Mouse IgG2a, kappa

Specificity: This antibody binds to human CD3.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogen: Human CD3

Isotype: IgG2a kappa

Application Details

Application Notes: This antibody competes for CD3 binding with the therapeutic antibody OKT3 (Ab00122). 12F6 binding to CD3 on human T-cells stimulates the secretion of TNF-alpha, INF-gamma and IL-10. Humanized versions of this antibody are also available.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD3 epsilon

Target: CD3 epsilon (CD3E)

Alternative Name: CD3 epsilon

Background: Leu4/T3, ET-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e

UniProt: P07766

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway