Recombinant CD38 antibody

Catalog No. ABIN5668195

This anti-CD38 antibody is a Rabbit Chimeric antibody detecting CD38 in FACS and IP. Suitable for Human.

Quick Overview for Recombinant CD38 antibody (ABIN5668195)

Target: CD38

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This CD38 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: HB7

Product Details anti-CD38 Antibody

Purpose: Anti-CD38 [HB7], Rabbit IgG, kappa

Specificity: This antibody binds to an epitope between amino acids 273-285 of human CD38, an approximately 45 kDa type II transmembrane protein, expressed on essentially all pre-B lymphocytes, plasma cells, and thymocytes. Also present on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. Bimodally expressed during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells. This antibody competes with clone AT13/5 (Ab00289) (Ellis 1995).

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: Viable cells (1 x 10E7) of the human cell line, BJAB (Human Burkitt lymphoma B cell line), which was were injected intraperitoneally into 8-week-old BALB/c mice.

Isotype: IgG kappa

Application Details

Application Notes: A customer reports successfully using this antibody (coupled to magnetic beads) for isolation of plasma cells from the intestinal lamina propria.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD38

Target: CD38

Background: ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase, EC 3.2.2.5, Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10, CD38, p45, NAD(+) nucleosidase

UniProt: P28907