Recombinant CD8 alpha antibody

Catalog No. ABIN5668208

This Rat Monoclonal antibody specifically detects CD8 alpha in FACS, IF, IHC (fro) and BR. It exhibits reactivity toward Mouse.

Quick Overview for Recombinant CD8 alpha antibody (ABIN5668208)

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD8 alpha antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)

Clone: YTS 105-18

Product Details anti-CD8 alpha Antibody

Purpose: Anti-CD8 alpha [YTS 105.18], Rat IgG2a, kappa

Specificity: Recognizes a non polymorphic epitope on the mouse CD8 alpha chain. This antibody has been reported to block MHC I dependent T cell responses in vitro and in vivo.

Characteristics:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogen: Ly-2-transfected mouse L cells.

Isotype: IgG2a kappa

Application Details

Application Notes: This antibody can be used to stain for murine CD8 and can be used to block interaction with CD8.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD8 alpha

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Alternative Name: CD8 alpha

Background: Lyt-2, CD8A Antibody, CD8a molecule Antibody, CD8a antigen Antibody, OKT8 T-cell antigen Antibody, Leu2 T-lymphocyte antigen Antibody, T8 T-cell antigen Antibody, T cell co-receptor Antibody, p32 Antibody, CD8 Antibody, Leu2 Antibody, T-cell antigen Leu2

UniProt: P01731

Pathways: TCR Signaling