Recombinant CD8 alpha antibody

Catalog No. ABIN5668209

The Rabbit Chimeric anti-CD8 alpha antibody has been validated for FACS, IF, IHC (fro) and BR. It is suitable to detect CD8 alpha in samples from Mouse.

Quick Overview for Recombinant CD8 alpha antibody (ABIN5668209)

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rabbit

Clonality: Chimeric

Conjugate: This CD8 alpha antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)

Clone: YTS 105-18

Product Details anti-CD8 alpha Antibody

Purpose: Anti-CD8 alpha [YTS 105.18], Rabbit IgG, kappa

Specificity: Recognizes a non polymorphic epitope on the mouse CD8 alpha chain. This antibody has been reported to block MHC I dependent T cell responses in vitro and in vivo.

Characteristics:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogen: Ly-2-transfected mouse L cells.

Isotype: IgG kappa

Application Details

Application Notes: This antibody can be used to stain for murine CD8 and can be used to block interaction with CD8.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD8 alpha

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Alternative Name: CD8 alpha

Background: Lyt-2, CD8A Antibody, CD8a molecule Antibody, CD8a antigen Antibody, OKT8 T-cell antigen Antibody, Leu2 T-lymphocyte antigen Antibody, T8 T-cell antigen Antibody, T cell co-receptor Antibody, p32 Antibody, CD8 Antibody, Leu2 Antibody, T-cell antigen Leu2

UniProt: P01731

Pathways: TCR Signaling