LRPPRC antibody (N-Term)

Catalog No. ABIN5671370

The Rabbit Polyclonal anti-LRPPRC antibody (ABIN5671370) specifically detects LRPPRC in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for LRPPRC antibody (N-Term) (ABIN5671370)

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRPPRC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LRPPRC Antibody

Binding Specificity: N-Term

Sequence: NEYKFSPTDF LAKMEEANIQ PNRVTYQRLI ASYCNVGDIE GASKILGFMK

Predicted Reactivity: Cow: 79%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against LPPRC. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LPPRC

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LRPPRC

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Alternative Name: LPPRC

Background: This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.

Alias Symbols: LRPPRC, LRP130,

Protein Interaction Partner: SPRTN, CEP76, HAUS2, CEP250, SART3, AURKB, TP53, AURKA, SUMO2, SUMO3, CDKN1A, IVNS1ABP, STAU1, UBC, MDM2, LGR4, ASB5, RNF2, EZH2, BMI1, PARK2, FBXO6, ADRB2, METTL22, vpu, ITGA4, FN1, C1QBP, VCAM1, PEX14, SMURF1, ILF3, CPS1, MRPS35, SEC23A, GRK5, UBD, CDK2

Protein Size: 1394

Gene ID: 10128

NCBI Accession: NP_573566

UniProt: P42704