LRPPRC antibody (N-Term)

Catalog No. ABIN5671370

This anti-LRPPRC antibody is a Rabbit Polyclonal antibody detecting LRPPRC in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for LRPPRC antibody (N-Term) (ABIN5671370)

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRPPRC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LRPPRC Antibody

Binding Specificity: N-Term

Sequence: NEYKFSPTDF LAKMEEANIQ PNRVTYQRLI ASYCNVGDIE GASKILGFMK

Predicted Reactivity: Cow: 79%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against LPPRC. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LPPRC

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LRPPRC

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Alternative Name: LPPRC

Background: This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.

Alias Symbols: LRPPRC, LRP130,

Protein Interaction Partner: SPRTN, CEP76, HAUS2, CEP250, SART3, AURKB, TP53, AURKA, SUMO2, SUMO3, CDKN1A, IVNS1ABP, STAU1, UBC, MDM2, LGR4, ASB5, RNF2, EZH2, BMI1, PARK2, FBXO6, ADRB2, METTL22, vpu, ITGA4, FN1, C1QBP, VCAM1, PEX14, SMURF1, ILF3, CPS1, MRPS35, SEC23A, GRK5, UBD, CDK2

Protein Size: 1394

Gene ID: 10128

NCBI Accession: NP_573566

UniProt: P42704