PHOX2B antibody (C-Term)

Catalog No. ABIN5671377

This Rabbit Polyclonal antibody specifically detects PHOX2B in WB. It exhibits reactivity toward Human.

Quick Overview for PHOX2B antibody (C-Term) (ABIN5671377)

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHOX2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHOX2B Antibody

Binding Specificity: C-Term

Sequence: RAAAAAAAAA KNGSSGKKSD SSRDDESKEA KSTDPDSTGG PGPNPNPTPS

Characteristics: This is a rabbit polyclonal antibody against PHX2B. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PHX2B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Alternative Name: PHX2B

Background: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element.

Alias Symbols: PHOX2B, PMX2B,

Protein Interaction Partner: UBC,

Protein Size: 314

Gene ID: 8929

NCBI Accession: NP_003915

UniProt: Q99453