PLOD1 antibody (C-Term)

Catalog No. ABIN5671398

This Rabbit Polyclonal antibody specifically detects PLOD1 in WB. It exhibits reactivity toward Human.

Quick Overview for PLOD1 antibody (C-Term) (ABIN5671398)

Target: PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLOD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLOD1 Antibody

Binding Specificity: C-Term

Sequence: DLAFVVRYKP DEQPSLMPHH DASTFTINIA LNRVGVDYEG GGCRFLRYNC

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PLOD1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLOD1

Target: PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))

Alternative Name: PLOD1

Background: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: LH, LH1, LLH, EDS6, PLOD

Protein Size: 727

Gene ID: 5351

NCBI Accession: NM_000302, NP_000293

UniProt: Q02809