TPRKB antibody (N-Term)

Catalog No. ABIN5671498

The Rabbit Polyclonal anti-TPRKB antibody has been validated for WB. It is suitable to detect TPRKB in samples from Human.

Quick Overview for TPRKB antibody (N-Term) (ABIN5671498)

Target: TPRKB (TP53RK Binding Protein (TPRKB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPRKB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TPRKB Antibody

Binding Specificity: N-Term

Sequence: LTHQLDLFPE CRVTLLLFKD VKNAGDLRRK AMEGTIDGSL INPTVIVDPF

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TPRKB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TPRKB

Target: TPRKB (TP53RK Binding Protein (TPRKB))

Alternative Name: TPRKB

Background: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.

Alias Symbols: CGI-121

Protein Size: 214

Gene ID: 51002

NCBI Accession: NM_016058, NP_057142