TMEM5 antibody (N-Term)

Catalog No. ABIN5671927

The Rabbit Polyclonal anti-TMEM5 antibody has been validated for WB. It is suitable to detect TMEM5 in samples from Mouse.

Quick Overview for TMEM5 antibody (N-Term) (ABIN5671927)

Target: TMEM5 (Transmembrane Protein 5 (TMEM5))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMEM5 Antibody

Binding Specificity: N-Term

Sequence: AAAAQAKERR GREQSALESE EWNPWEGDEK NEQRHRVKTN LQILNKSTKE

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse TMEM5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TMEM5

Target: TMEM5 (Transmembrane Protein 5 (TMEM5))

Alternative Name: TMEM5

Background: UDP-xylosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Acts as a UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase, which catalyzes the transfer of UDP-D-xylose to ribitol 5-phosphate (Rbo5P) to form the Xylbeta1-4Rbo5P linkage on O-mannosyl glycan.

Alias Symbols: 6330415D21Rik

Protein Size: 444

Gene ID: 216395

NCBI Accession: NM_153059, NP_694699

UniProt: Q8VDX6