Histone H1.3 antibody (C-Term)

Catalog No. ABIN5673178

The Rabbit Polyclonal anti-Histone H1.3 antibody has been validated for WB. It is suitable to detect Histone H1.3 in samples from Human.

Quick Overview for Histone H1.3 antibody (C-Term) (ABIN5673178)

Target: Histone H1.3 (HIST1H1D)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H1.3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Histone H1.3 Antibody

Binding Specificity: C-Term

Sequence: ATAAGTKKVA KSAKKVKTPQ PKKAAKSPAK AKAPKPKAAK PKSGKPKVTK

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HIST1H1D

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Histone H1.3

Target: Histone H1.3 (HIST1H1D)

Alternative Name: HIST1H1D

Background: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Alias Symbols: H1D, H1.3, H1F3, H1s-2

Protein Size: 221

Gene ID: 3007

NCBI Accession: NM_005320, NP_005311

UniProt: P16402