PLSCR3 antibody (N-Term)

Catalog No. ABIN5673452

This anti-PLSCR3 antibody is a Rabbit Polyclonal antibody detecting PLSCR3 in WB. Suitable for Human.

Quick Overview for PLSCR3 antibody (N-Term) (ABIN5673452)

Target: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLSCR3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLSCR3 Antibody

Binding Specificity: N-Term

Sequence: PPKGYAPSPP PPYPVTPGYP EPALHPGPGQ APVPAQVPAP APGFALFPSP

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PLSCR3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLSCR3

Target: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Alternative Name: PLSCR3

Background: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.

Protein Size: 295

Gene ID: 57048

NCBI Accession: NM_001201576, NP_001188505

UniProt: Q9NRY6

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis