Corneodesmosin antibody (C-Term)

Catalog No. ABIN5674011

This Rabbit Polyclonal antibody specifically detects Corneodesmosin in WB. It exhibits reactivity toward Human.

Quick Overview for Corneodesmosin antibody (C-Term) (ABIN5674011)

Target: Corneodesmosin (CDSN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Corneodesmosin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Corneodesmosin Antibody

Binding Specificity: C-Term

Sequence: LTLTGGPDGS PHPDPSAGAK PCGSSSAGKI PCRSIRDILA QVKPLGPQLA

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDSN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Corneodesmosin

Target: Corneodesmosin (CDSN)

Alternative Name: CDSN

Background: This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. The encoded protein undergoes a series of cleavages during corneocyte maturation. This gene is highly polymorphic in human populations, and variation has been associated with skin diseases such as psoriasis, hypotrichosis and peeling skin syndrome. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6.

Alias Symbols: S, PSS, HTSS, PSS1, HTSS1, HYPT2

Protein Size: 529

Gene ID: 1041

NCBI Accession: NM_001264, NP_001255

UniProt: Q15517