DRD3 antibody (3rd Cytoplasmic Domain)

Catalog No. ABIN5674035

This Rabbit Polyclonal antibody specifically detects DRD3 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for DRD3 antibody (3rd Cytoplasmic Domain) (ABIN5674035)

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-DRD3 Antibody

Binding Specificity: 3rd Cytoplasmic Domain

Specificity: The 19 AA human D3R peptide showed no significant sequence homology with other dopamine receptors (D1, D2, D4 or D5). It has sequence homology of 94 % with monkey (18/19 AA) and 73 % with mouse/rat (14/19 AA) D3R receptors (1-2). Antibody cross-reactivity with D3R from various species is not known.

Purification: Immunoaffinity purified

Immunogen: A 19 AA Peptide (Control peptide) sequence from the human D3 receptor within the 3rd cytoplasmic domain. The peptide was coupled to KLH.

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (0.5 - 1 μg/mL), IHC (2 - 10 μg/mL), WB (1 - 10 μg/mL)

Usage: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Western Blot: 1-10 μg/mL. Using ECL. ELISA: 0.5-1 μg/mL. Control peptide can be used to coat ELISA plates at 1 μg/mL. Immunohistochemistry: 2-10 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % BSA, 0.1 % sodium azide, 40 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for DRD3

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Alternative Name: DRD3 / Dopamine Receptor D3

Background: Name/Gene ID: DRD3
Subfamily: Dopamine
Family: GPCR

Synonyms: DRD3, D3 dopamine receptor, D3DR, Dopamine 3 receptor, Dopamine receptor D3, D3nf, Essential tremor 1, ETM1, FET1, D(3) dopamine receptor, Dopamine D3 receptor

Gene ID: 1814

UniProt: P35462

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity