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SMAD2 antibody (pSer250)

This Rabbit Polyclonal antibody specifically detects SMAD2 in WB and ELISA. It exhibits reactivity toward Mouse and Rat.
Catalog No. ABIN5675082

Quick Overview for SMAD2 antibody (pSer250) (ABIN5675082)

Target

See all SMAD2 Antibodies
SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

Reactivity

  • 262
  • 166
  • 131
  • 14
  • 13
  • 10
  • 9
  • 8
  • 8
  • 7
  • 7
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  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Mouse, Rat

Host

  • 266
  • 15
  • 1
Rabbit

Clonality

  • 231
  • 51
Polyclonal

Conjugate

  • 139
  • 19
  • 13
  • 10
  • 7
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  • 6
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  • 5
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  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
This SMAD2 antibody is un-conjugated

Application

  • 224
  • 102
  • 71
  • 58
  • 55
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  • 53
  • 38
  • 29
  • 24
  • 14
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  • 5
  • 3
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  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • Binding Specificity

    • 55
    • 44
    • 29
    • 28
    • 24
    • 22
    • 9
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
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    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer250

    Cross-Reactivity

    Mouse, Rat

    Predicted Reactivity

    Human,Dog,Cow,Pig

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Anti-phospho-Smad2 (Ser250)

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    ELISA 1:500-1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Expiry Date

    12 months
  • Target

    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

    Alternative Name

    Smad2

    Background

    Synonyms: Mothers against decapentaplegic homolog 2, SMAD2, MAD homolog 2, Mothers against DPP homolog 2, JV18-1, Mad-related protein 2, hMAD-2, SMAD family member 2, MADH2, MADR2

    Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.

    Gene ID

    4087

    UniProt

    Q15796

    Pathways

    Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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