SMYD1 antibody (AA 31-130)

Catalog No. ABIN5675100

This Rabbit Polyclonal antibody specifically detects SMYD1 in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) and ICC. It exhibits reactivity toward Mouse.

Quick Overview for SMYD1 antibody (AA 31-130) (ABIN5675100)

Target: SMYD1 (SET and MYND Domain Containing 1 (SMYD1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMYD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-SMYD1 Antibody

Binding Specificity: AA 31-130

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SMYD1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SMYD1

Target: SMYD1 (SET and MYND Domain Containing 1 (SMYD1))

Alternative Name: SMYD1

Background:

Synonyms: Histone-lysine N-methyltransferase SMYD1, SMYD1, SET and MYND domain-containing protein 1

Background: Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.

Gene ID: 150572

UniProt: Q8NB12

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development