GPR75 antibody (AA 151-250)

Catalog No. ABIN5675305

The Rabbit Polyclonal anti-GPR75 antibody has been validated for WB, ELISA, IHC (p), ICC, IF (cc), IF (p) and IHC (fro). It is suitable to detect GPR75 in samples from Mouse.

Quick Overview for GPR75 antibody (AA 151-250) (ABIN5675305)

Target: GPR75 (G Protein-Coupled Receptor 75 (GPR75))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR75 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GPR75 Antibody

Binding Specificity: AA 151-250

Cross-Reactivity: Mouse

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPCR GPR75

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GPR75

Target: GPR75 (G Protein-Coupled Receptor 75 (GPR75))

Alternative Name: GPR75

Background:

Synonyms: Probable G-protein coupled receptor 75, GPR75,

Background: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

Gene ID: 10936

UniProt: O95800