MLZE antibody (AA 1-100)

Catalog No. ABIN5675323

The Rabbit Polyclonal anti-MLZE antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (p), ICC and IHC (fro). It is suitable to detect MLZE in samples from Human.

Quick Overview for MLZE antibody (AA 1-100) (ABIN5675323)

Target: MLZE (Melanomaderived Leucine Zipper Extra-Nuclear Factor (MLZE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLZE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MLZE Antibody

Binding Specificity: AA 1-100

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GSDMC

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MLZE

Target: MLZE (Melanomaderived Leucine Zipper Extra-Nuclear Factor (MLZE))

Alternative Name: GSDMC

Background:

Synonyms: Gasdermin C, Gasdermin-C, GSDMC, GSDMC_HUMAN, Melanoma derived leucine zipper, extra nuclear factor, Melanoma-derived leucine zipper-containing extranuclear factor, MLZE

Background: The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable).

Gene ID: 56169

UniProt: Q9BYG8