MLZE antibody (AA 1-100) (HRP)

Catalog No. ABIN5675325

This Rabbit Polyclonal antibody specifically detects MLZE in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for MLZE antibody (AA 1-100) (HRP) (ABIN5675325)

Target: MLZE (Melanomaderived Leucine Zipper Extra-Nuclear Factor (MLZE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLZE antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MLZE Antibody (HRP)

Binding Specificity: AA 1-100

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GSDMC

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MLZE

Target: MLZE (Melanomaderived Leucine Zipper Extra-Nuclear Factor (MLZE))

Alternative Name: GSDMC

Background:

Synonyms: Gasdermin C, Gasdermin-C, GSDMC, GSDMC_HUMAN, Melanoma derived leucine zipper, extra nuclear factor, Melanoma-derived leucine zipper-containing extranuclear factor, MLZE

Background: The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable).

Gene ID: 56169

UniProt: Q9BYG8