CELF3 antibody (AA 401-465)

Catalog No. ABIN5675511

This Rabbit Polyclonal antibody specifically detects CELF3 in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) and ICC. It exhibits reactivity toward Human.

Quick Overview for CELF3 antibody (AA 401-465) (ABIN5675511)

Target: CELF3 (CUGBP, Elav-Like Family Member 3 (CELF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CELF3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-CELF3 Antibody

Binding Specificity: AA 401-465

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CELF3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CELF3

Target: CELF3 (CUGBP, Elav-Like Family Member 3 (CELF3))

Alternative Name: CELF3

Background:

Synonyms: Bruno-like protein 1, BRUNOL1, CAG repeat protein 4, CAGH4, CELF-3, CELF3, CELF3_HUMAN, CUG-BP- and ETR-3-like factor 3, CUGBP Elav-like family member 3, ELAV-type RNA-binding protein 1, ERDA4, ETR-1, Expanded repeat domain protein CAG/CTG 4, RNA-binding protein BRUNOL-1, TNRC4, Trinucleotide repeat-containing gene 4 protein.

Background: RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.

Gene ID: 11189

UniProt: Q5SZQ8