CELF3 antibody (AA 401-465) (Biotin)

Catalog No. ABIN5675512

The Rabbit Polyclonal anti-CELF3 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect CELF3 in samples from Human.

Quick Overview for CELF3 antibody (AA 401-465) (Biotin) (ABIN5675512)

Target: CELF3 (CUGBP, Elav-Like Family Member 3 (CELF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CELF3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CELF3 Antibody (Biotin)

Binding Specificity: AA 401-465

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CELF3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CELF3

Target: CELF3 (CUGBP, Elav-Like Family Member 3 (CELF3))

Alternative Name: CELF3

Background:

Synonyms: Bruno-like protein 1, BRUNOL1, CAG repeat protein 4, CAGH4, CELF-3, CELF3, CELF3_HUMAN, CUG-BP- and ETR-3-like factor 3, CUGBP Elav-like family member 3, ELAV-type RNA-binding protein 1, ERDA4, ETR-1, Expanded repeat domain protein CAG/CTG 4, RNA-binding protein BRUNOL-1, TNRC4, Trinucleotide repeat-containing gene 4 protein.

Background: RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.

Gene ID: 11189

UniProt: Q5SZQ8