TUBB2B antibody

Catalog No. ABIN567612

Product Details anti-TUBB2B Antibody

Target: TUBB2B (Tubulin, beta 2B (TUBB2B))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBB2B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: The antibody recognizes Human and Mouse TUBB2B. Other species not tested.

Purification: Protein-G affinity chromatography

Clone: AT5B3

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for TUBB2B

Target: TUBB2B (Tubulin, beta 2B (TUBB2B))

Alternative Name: TUBB2B (TUBB2B Products)

Background: The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. Multiple beta Tubulin isoforms have been characterized and are expressed in mammalian tissues. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB2b is mainly expressed in developing neurons with a dominant expression during the critical steps of corticogenesis. Also, TUBB2B is a new critical gene involved in neuronal migration. It is present in the nuclei and nucleoplasm, Defects in this gene are a cause of asymmetric polymicrogyria.Synonyms: RP11-506K6.1, Tubulin beta-2B chain, beta II Tubulin B, beta-Tubulin

Gene ID: 347733

Pathways: Microtubule Dynamics