TNFRSF11A antibody (AA 30-212)
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- Target See all TNFRSF11A Antibodies
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
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Binding Specificity
- AA 30-212
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TNFRSF11A antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- TNFRSF11A Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human TNFRSF11A (AA: 30-212) expressed in E. Coli.
- Clone
- 8H8B2
- Isotype
- IgG1
- Top Product
- Discover our top product TNFRSF11A Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
- Alternative Name
- TNFRSF11A (TNFRSF11A Products)
- Background
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Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
Aliases: FEO, OFE, ODFR, OSTS, PDB2, RANK, CD265, OPTB7, TRANCER, LOH18CR1
- Molecular Weight
- 66kDa
- Gene ID
- 8792
- HGNC
- 353514
- UniProt
- Q9Y6Q6
- Pathways
- NF-kappaB Signaling
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