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NEFH antibody

The Chicken Polyclonal anti-NEFH antibody has been validated for WB and IHC. It is suitable to detect NEFH in samples from Human, Rat, Mouse and Chicken.
Catalog No. ABIN5687473

Quick Overview for NEFH antibody (ABIN5687473)

Target

See all NEFH Antibodies
NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Reactivity

  • 127
  • 96
  • 75
  • 59
  • 41
  • 33
  • 24
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  • 13
  • 13
  • 9
  • 9
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  • 1
  • 1
Human, Rat, Mouse, Chicken

Host

  • 81
  • 63
  • 8
Chicken

Clonality

  • 99
  • 53
Polyclonal

Conjugate

  • 95
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NEFH antibody is un-conjugated

Application

  • 100
  • 60
  • 48
  • 31
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  • 24
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  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Specificity

    Specific for the ~200k Neurofilament H protein.

    Purification

    Total IgY fraction

    Immunogen

    Purified bovine NF-H.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Storage

    -20 °C

    Storage Comment

    Neurofilament NF-H antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • Target

    NEFH (Neurofilament, Heavy Polypeptide (NEFH))

    Alternative Name

    Neurofilament NF-H

    Background

    Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.

    Molecular Weight

    200 kDa

    Gene ID

    4744

    UniProt

    P12036
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